TSPAN9-DNM1L Fusion FISH Probe
The TSPAN9-DNM1L Fusion FISH Probe is used to confirm a fusion of the TSPAN9 and DNM1L genes. The fusion of the TSPAN9 and DNM1L genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN9-DNM1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN9-DNM1L-20-AQAQ | 20 (40 μL) | 200 μL |
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DNM1L Gene Summary
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
Gene Name: Dynamin 1 Like
Chromosome: CHR12: 32832136 -32898584
Locus: 12p11.21
TSPAN9 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. Alternatively spliced transcripts encoding the same protein have been identified. [provided by RefSeq, Nov 2009]
Gene Name: Tetraspanin 9
Chromosome: CHR12: 3186520 -3395730
Locus: 12p13.33-p13.32
Gene Diseases
The TSPAN9 DNM1L Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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