TSPAN8-HSP90B1 Fusion FISH Probe
The TSPAN8-HSP90B1 Fusion FISH Probe is used to confirm a fusion of the TSPAN8 and HSP90B1 genes. The fusion of the TSPAN8 and HSP90B1 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN8-HSP90B1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN8-HSP90B1-20-AQAQ | 20 (40 μL) | 200 μL |
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TSPAN8 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 8
Chromosome: CHR12: 71518876 -71551779
Locus: 12q21.1
HSP90B1 Gene Summary
This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]
Gene Name: Heat Shock Protein 90 Beta Family Member 1
Chromosome: CHR12: 104324188 -104341703
Locus: 12q23.3
Gene Diseases
The TSPAN8 HSP90B1 Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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