TSPAN5-PKD2 Fusion FISH Probe
The TSPAN5-PKD2 Fusion FISH Probe is used to confirm a fusion of the TSPAN5 and PKD2 genes. The fusion of the TSPAN5 and PKD2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN5-PKD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN5-PKD2-20-AQAQ | 20 (40 μL) | 200 μL |
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PKD2 Gene Summary
This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. [provided by RefSeq, Mar 2011]
Gene Name: Polycystin 2, Transient Receptor Potential Cation Channel
Chromosome: CHR4: 88928798 -88998931
Locus: 4q22.1
TSPAN5 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 5
Chromosome: CHR4: 99391517 -99579812
Locus: 4q23
Gene Diseases
The TSPAN5 PKD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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