TSPAN4-TALDO1 Fusion FISH Probe
The TSPAN4-TALDO1 Fusion FISH Probe is used to confirm a fusion of the TSPAN4 and TALDO1 genes. The fusion of the TSPAN4 and TALDO1 genes has been associated with Kidney Renal Papillary Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN4-TALDO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN4-TALDO1-20-AQAQ | 20 (40 μL) | 200 μL |
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TALDO1 Gene Summary
Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Gene Name: Transaldolase 1
Chromosome: CHR11: 747431 -765024
Locus: 11p15.5
TSPAN4 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 4
Chromosome: CHR11: 842823 -867116
Locus: 11p15.5
Gene Diseases
The TSPAN4 TALDO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Kidney Renal Papillary Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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