TSPAN15-VPS26A Fusion FISH Probe
The TSPAN15-VPS26A Fusion FISH Probe is used to confirm a fusion of the TSPAN15 and VPS26A genes. The fusion of the TSPAN15 and VPS26A genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN15-VPS26A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN15-VPS26A-20-AQAQ | 20 (40 μL) | 200 μL |
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VPS26A Gene Summary
This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: VPS26, Retromer Complex Component A
Chromosome: CHR10: 70883907 -70932616
Locus: 10q22.1
TSPAN15 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 15
Chromosome: CHR10: 71211225 -71267423
Locus: 10q22.1
Gene Diseases
The TSPAN15 VPS26A Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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