TSPAN15-HK1 Fusion FISH Probe
The TSPAN15-HK1 Fusion FISH Probe is used to confirm a fusion of the TSPAN15 and HK1 genes. The fusion of the TSPAN15 and HK1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN15-HK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN15-HK1-20-AQAQ | 20 (40 μL) | 200 μL |
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HK1 Gene Summary
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific. [provided by RefSeq, Apr 2016]
Gene Name: Hexokinase 1
Chromosome: CHR10: 71029755 -71161637
Locus: 10q22.1
TSPAN15 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 15
Chromosome: CHR10: 71211225 -71267423
Locus: 10q22.1
Gene Diseases
The TSPAN15 HK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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