TSPAN1-USP20 Fusion FISH Probe
The TSPAN1-USP20 Fusion FISH Probe is used to confirm a fusion of the TSPAN1 and USP20 genes. The fusion of the TSPAN1 and USP20 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSPAN1-USP20-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-RERE | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-REOR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-REGO | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-REGR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-REAQ | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-ORRE | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-OROR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-ORGO | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GORE | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GOOR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GOGO | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GOGR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GRRE | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GROR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GRGO | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GRGR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-AQRE | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-AQOR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-AQGO | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-AQGR | 20 (40 μL) | 200 μL |
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| TSPAN1-USP20-20-AQAQ | 20 (40 μL) | 200 μL |
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TSPAN1 Gene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]
Gene Name: Tetraspanin 1
Chromosome: CHR1: 46640748 -46651634
Locus: 1p34.1
USP20 Gene Summary
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
Gene Name: Ubiquitin Specific Peptidase 20
Chromosome: CHR9: 132597695 -132644107
Locus: 9q34.11
Gene Diseases
The TSPAN1 USP20 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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