TSHZ3-CEACAM7 Fusion FISH Probe
The TSHZ3-CEACAM7 Fusion FISH Probe is used to confirm a fusion of the TSHZ3 and CEACAM7 genes. The fusion of the TSHZ3 and CEACAM7 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSHZ3-CEACAM7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-RERE | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-REOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-REGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-REGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-REAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-ORRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-OROR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-ORGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GORE | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GOOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GOGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GOGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GRRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GROR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GRGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GRGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-AQRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-AQOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-AQGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-AQGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CEACAM7-20-AQAQ | 20 (40 μL) | 200 μL |
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CEACAM7 Gene Summary
This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
Gene Name: Carcinoembryonic Antigen Related Cell Adhesion Molecule 7
Chromosome: CHR19: 42177234 -42192096
Locus: 19q13.2
TSHZ3 Gene Summary
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016]
Gene Name: Teashirt Zinc Finger Homeobox 3
Chromosome: CHR19: 31765850 -31840190
Locus: 19q12
Gene Diseases
The TSHZ3 CEACAM7 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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