TSHZ3-CDH2 Fusion FISH Probe
The TSHZ3-CDH2 Fusion FISH Probe is used to confirm a fusion of the TSHZ3 and CDH2 genes. The fusion of the TSHZ3 and CDH2 genes has been associated with Pancreatic Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSHZ3-CDH2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-RERE | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-REOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-REGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-REGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-REAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-ORRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-OROR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-ORGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GORE | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GOOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GOGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GOGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GRRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GROR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GRGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GRGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-AQRE | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-AQOR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-AQGO | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-AQGR | 20 (40 μL) | 200 μL |
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| TSHZ3-CDH2-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH2 Gene Summary
This gene encodes a classical cadherin and member of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein is proteolytically processed to generate a calcium-dependent cell adhesion molecule and glycoprotein. This protein plays a role in the establishment of left-right asymmetry, development of the nervous system and the formation of cartilage and bone. [provided by RefSeq, Nov 2015]
Gene Name: Cadherin 2
Chromosome: CHR18: 25530929 -25757445
Locus: 18q12.1
TSHZ3 Gene Summary
This gene encodes a zinc-finger transcription factor that regulates smooth muscle cell differentiation in the developing urinary tract. Consistent with this role, mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis. The encoded transcription factor comprises a gene silencing complex that inhibits caspase expression. Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients. [provided by RefSeq, Jul 2016]
Gene Name: Teashirt Zinc Finger Homeobox 3
Chromosome: CHR19: 31765850 -31840190
Locus: 19q12
Gene Diseases
The TSHZ3 CDH2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pancreatic Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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