TSC22D1-NUFIP1 Fusion FISH Probe
The TSC22D1-NUFIP1 Fusion FISH Probe is used to confirm a fusion of the TSC22D1 and NUFIP1 genes. The fusion of the TSC22D1 and NUFIP1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSC22D1-NUFIP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-RERE | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-REOR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-REGO | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-REGR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-OROR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GORE | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GROR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSC22D1-NUFIP1-20-AQAQ | 20 (40 μL) | 200 μL |
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TSC22D1 Gene Summary
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Gene Name: TSC22 Domain Family Member 1
Chromosome: CHR13: 45006278 -45150701
Locus: 13q14.11
NUFIP1 Gene Summary
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012]
Gene Name: NUFIP1, FMR1 Interacting Protein 1
Chromosome: CHR13: 45513383 -45563613
Locus: 13q14.12
Gene Diseases
The TSC22D1 NUFIP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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