TSC22D1-DNAJC5B Fusion FISH Probe
The TSC22D1-DNAJC5B Fusion FISH Probe is used to confirm a fusion of the TSC22D1 and DNAJC5B genes. The fusion of the TSC22D1 and DNAJC5B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSC22D1-DNAJC5B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-RERE | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-REOR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-REGO | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-REGR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-REAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-ORRE | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-OROR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-ORGO | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GORE | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GOOR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GOGO | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GOGR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GRRE | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GROR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GRGO | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GRGR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-AQRE | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-AQOR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-AQGO | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-AQGR | 20 (40 μL) | 200 μL |
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| TSC22D1-DNAJC5B-20-AQAQ | 20 (40 μL) | 200 μL |
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TSC22D1 Gene Summary
This gene encodes a member of the TSC22 domain family of leucine zipper transcription factors. The encoded protein is stimulated by transforming growth factor beta, and regulates the transcription of multiple genes including C-type natriuretic peptide. The encoded protein may play a critical role in tumor suppression through the induction of cancer cell apoptosis, and a single nucleotide polymorphism in the promoter of this gene has been associated with diabetic nephropathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Gene Name: TSC22 Domain Family Member 1
Chromosome: CHR13: 45006278 -45150701
Locus: 13q14.11
DNAJC5B Gene Summary
This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins that is characterized by an N-terminal DNAJ domain, a linker region, and a cysteine-rich C-terminal domain. The encoded protein, together with heat shock protein 70, is thought to regulate the proper folding of other proteins. The orthologous mouse protein is membrane-associated and is targeted to the trans-golgi network. [provided by RefSeq, Mar 2017]
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C5 Beta
Chromosome: CHR8: 66933790 -67012755
Locus: 8q13.1
Gene Diseases
The TSC22D1 DNAJC5B Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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