TSC1-DOLPP1 Fusion FISH Probe
The TSC1-DOLPP1 Fusion FISH Probe is used to confirm a fusion of the TSC1 and DOLPP1 genes. The fusion of the TSC1 and DOLPP1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TSC1-DOLPP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-RERE | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-REOR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-REGO | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-REGR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-REAQ | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-ORRE | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-OROR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-ORGO | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GORE | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GOOR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GOGO | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GOGR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GRRE | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GROR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GRGO | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GRGR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-AQRE | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-AQOR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-AQGO | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-AQGR | 20 (40 μL) | 200 μL |
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| TSC1-DOLPP1-20-AQAQ | 20 (40 μL) | 200 μL |
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TSC1 Gene Summary
This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Gene Name: TSC Complex Subunit 1
Chromosome: CHR9: 135766734 -135820020
Locus: 9q34.13
DOLPP1 Gene Summary
A similar gene has been characterized in mice and encodes dolichyl pyrophosphate (Dol-P-P) phosphatase. This protein dephosphorylates dolichyl pyrophosphate so that it may be re-utilized as a glycosyl carrier lipid by the oligosaccharyltransferase multisubunit complex in the ER. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Gene Name: Dolichyldiphosphatase 1
Chromosome: CHR9: 131843382 -131852717
Locus: 9q34.11
Gene Diseases
The TSC1 DOLPP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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