TRPV6-KEL Fusion FISH Probe
The TRPV6-KEL Fusion FISH Probe is used to confirm a fusion of the TRPV6 and KEL genes. The fusion of the TRPV6 and KEL genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRPV6-KEL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-RERE | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-REOR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-REGO | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-REGR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-REAQ | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-ORRE | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-OROR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-ORGO | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GORE | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GOOR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GOGO | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GOGR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GRRE | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GROR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GRGO | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GRGR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-AQRE | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-AQOR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-AQGO | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-AQGR | 20 (40 μL) | 200 μL |
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| TRPV6-KEL-20-AQAQ | 20 (40 μL) | 200 μL |
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KEL Gene Summary
This gene encodes a type II transmembrane glycoprotein that is the highly polymorphic Kell blood group antigen. The Kell glycoprotein links via a single disulfide bond to the XK membrane protein that carries the Kx antigen. The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases. [provided by RefSeq, Jul 2008]
Gene Name: Kell Blood Group, Metallo-endopeptidase
Chromosome: CHR7: 142638200 -142659503
Locus: 7q34
TRPV6 Gene Summary
This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015]
Gene Name: Transient Receptor Potential Cation Channel Subfamily V Member 6
Chromosome: CHR7: 142568959 -142583477
Locus: 7q34
Gene Diseases
The TRPV6 KEL Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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