TRPV3-UBE2G1 Fusion FISH Probe
The TRPV3-UBE2G1 Fusion FISH Probe is used to confirm a fusion of the TRPV3 and UBE2G1 genes. The fusion of the TRPV3 and UBE2G1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRPV3-UBE2G1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-RERE | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-REOR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-REGO | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-REGR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-REAQ | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-ORRE | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-OROR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-ORGO | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GORE | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GOOR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GOGO | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GOGR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GRRE | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GROR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GRGO | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GRGR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-AQRE | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-AQOR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-AQGO | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-AQGR | 20 (40 μL) | 200 μL |
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| TRPV3-UBE2G1-20-AQAQ | 20 (40 μL) | 200 μL |
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UBE2G1 Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 G1
Chromosome: CHR17: 4172511 -4269969
Locus: 17p13.2
TRPV3 Gene Summary
This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Transient Receptor Potential Cation Channel Subfamily V Member 3
Chromosome: CHR17: 3416485 -3461289
Locus: 17p13.2
Gene Diseases
The TRPV3 UBE2G1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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