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TRMU-TMEM184B Fusion FISH Probe

The TRMU-TMEM184B Fusion FISH Probe is used to confirm a fusion of the TRMU and TMEM184B genes. The fusion of the TRMU and TMEM184B genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TRMU-TMEM184B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TRMU-TMEM184B-20-RERE 20 (40 μL) 200 μL
TRMU-TMEM184B-20-REOR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-REGO 20 (40 μL) 200 μL
TRMU-TMEM184B-20-REGR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-REAQ 20 (40 μL) 200 μL
TRMU-TMEM184B-20-ORRE 20 (40 μL) 200 μL
TRMU-TMEM184B-20-OROR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-ORGO 20 (40 μL) 200 μL
TRMU-TMEM184B-20-ORAQ 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GORE 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GOOR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GOGO 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GOGR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GOAQ 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GRRE 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GROR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GRGO 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GRGR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-GRAQ 20 (40 μL) 200 μL
TRMU-TMEM184B-20-AQRE 20 (40 μL) 200 μL
TRMU-TMEM184B-20-AQOR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-AQGO 20 (40 μL) 200 μL
TRMU-TMEM184B-20-AQGR 20 (40 μL) 200 μL
TRMU-TMEM184B-20-AQAQ 20 (40 μL) 200 μL

TMEM184B Gene Summary

The Transmembrane Protein 184B (TMEM184B) gene is located on chr22 :38615297-38669040 at 22q13.1.

Gene Name: Transmembrane Protein 184B

Chromosome: CHR22: 38615297 -38669040

Locus: 22q13.1

TRMU Gene Summary

This nuclear gene encodes a mitochondrial tRNA-modifying enzyme. The encoded protein catalyzes the 2-thiolation of uridine on the wobble positions of tRNA(Lys), tRNA(Glu), and tRNA(Gln), resulting in the formation of 5-taurinomethyl-2-thiouridine moieties. Mutations in this gene may cause transient infantile liver failure. Polymorphisms in this gene may also influence the severity of deafness caused by mitochondrial 12S ribosomal RNA mutations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Name: TRNA 5-methylaminomethyl-2-thiouridylate Methyltransferase

Chromosome: CHR22: 46731297 -46753237

Locus: 22q13.31

Gene Diseases

The TRMU TMEM184B Fusion has been associated with the following diseases:

Disease Name
Liver Hepatocellular Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.