TRIT1-CHI3L2 Fusion FISH Probe
The TRIT1-CHI3L2 Fusion FISH Probe is used to confirm a fusion of the TRIT1 and CHI3L2 genes. The fusion of the TRIT1 and CHI3L2 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIT1-CHI3L2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-RERE | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-REOR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-REGO | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-REGR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-OROR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GORE | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GROR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIT1-CHI3L2-20-AQAQ | 20 (40 μL) | 200 μL |
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CHI3L2 Gene Summary
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Chitinase 3 Like 2
Chromosome: CHR1: 111770280 -111786062
Locus: 1p13.2
TRIT1 Gene Summary
This gene encodes a protein that that is targeted to the mitochondrion and modifies transfer RNAs (tRNAs) by adding a dimethylallyl group onto the adenine at position 37. This modification is important for maintaining the correct reading frame during protein translation. This gene is considered a tumor suppressor and its expression can decrease cell growth. Alternative splicing results in multiple transcripts variants, most of which are likely non-functional. [provided by RefSeq, Aug 2015]
Gene Name: TRNA Isopentenyltransferase 1
Chromosome: CHR1: 40306705 -40349177
Locus: 1p34.2
Gene Diseases
The TRIT1 CHI3L2 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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