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TRIP12-KIF1A Fusion FISH Probe

The TRIP12-KIF1A Fusion FISH Probe is used to confirm a fusion of the TRIP12 and KIF1A genes. The fusion of the TRIP12 and KIF1A genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TRIP12-KIF1A-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TRIP12-KIF1A-20-RERE 20 (40 μL) 200 μL
TRIP12-KIF1A-20-REOR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-REGO 20 (40 μL) 200 μL
TRIP12-KIF1A-20-REGR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-REAQ 20 (40 μL) 200 μL
TRIP12-KIF1A-20-ORRE 20 (40 μL) 200 μL
TRIP12-KIF1A-20-OROR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-ORGO 20 (40 μL) 200 μL
TRIP12-KIF1A-20-ORAQ 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GORE 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GOOR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GOGO 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GOGR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GOAQ 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GRRE 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GROR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GRGO 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GRGR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-GRAQ 20 (40 μL) 200 μL
TRIP12-KIF1A-20-AQRE 20 (40 μL) 200 μL
TRIP12-KIF1A-20-AQOR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-AQGO 20 (40 μL) 200 μL
TRIP12-KIF1A-20-AQGR 20 (40 μL) 200 μL
TRIP12-KIF1A-20-AQAQ 20 (40 μL) 200 μL

KIF1A Gene Summary

The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]

Gene Name: Kinesin Family Member 1A

Chromosome: CHR2: 241653180 -241759725

Locus: 2q37.3

TRIP12 Gene Summary

The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]

Gene Name: Thyroid Hormone Receptor Interactor 12

Chromosome: CHR2: 230631929 -230786655

Locus: 2q36.3

Gene Diseases

The TRIP12 KIF1A Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.