TRIP12-KIF1A Fusion FISH Probe
The TRIP12-KIF1A Fusion FISH Probe is used to confirm a fusion of the TRIP12 and KIF1A genes. The fusion of the TRIP12 and KIF1A genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIP12-KIF1A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-RERE | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-REOR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-REGO | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-REGR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-OROR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GORE | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GROR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIP12-KIF1A-20-AQAQ | 20 (40 μL) | 200 μL |
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KIF1A Gene Summary
The protein encoded by this gene is a member of the kinesin family and functions as an anterograde motor protein that transports membranous organelles along axonal microtubules. Mutations at this locus have been associated with spastic paraplegia-30 and hereditary sensory neuropathy IIC. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012]
Gene Name: Kinesin Family Member 1A
Chromosome: CHR2: 241653180 -241759725
Locus: 2q37.3
TRIP12 Gene Summary
The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]
Gene Name: Thyroid Hormone Receptor Interactor 12
Chromosome: CHR2: 230631929 -230786655
Locus: 2q36.3
Gene Diseases
The TRIP12 KIF1A Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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