TRIP12-ITM2C Fusion FISH Probe
The TRIP12-ITM2C Fusion FISH Probe is used to confirm a fusion of the TRIP12 and ITM2C genes. The fusion of the TRIP12 and ITM2C genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIP12-ITM2C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-RERE | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-REOR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-REGO | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-REGR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-OROR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GORE | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GROR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIP12-ITM2C-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIP12 Gene Summary
The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53. [provided by RefSeq, Jan 2017]
Gene Name: Thyroid Hormone Receptor Interactor 12
Chromosome: CHR2: 230631929 -230786655
Locus: 2q36.3
ITM2C Gene Summary
The Integral Membrane Protein 2C (ITM2C) gene is located on chr2 :231729620-231743963 at 2q37.1.
Gene Name: Integral Membrane Protein 2C
Chromosome: CHR2: 231729620 -231743963
Locus: 2q37.1
Gene Diseases
The TRIP12 ITM2C Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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