TRIOBP-UNC13C Fusion FISH Probe
The TRIOBP-UNC13C Fusion FISH Probe is used to confirm a fusion of the TRIOBP and UNC13C genes. The fusion of the TRIOBP and UNC13C genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIOBP-UNC13C-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-RERE | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-REOR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-REGO | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-REGR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-OROR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GORE | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GROR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIOBP-UNC13C-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIOBP Gene Summary
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]
Gene Name: TRIO And F-actin Binding Protein
Chromosome: CHR22: 38092994 -38172563
Locus: 22q13.1
UNC13C Gene Summary
The Unc-13 Homolog C (UNC13C) gene is located on chr15 :54305100-54920806 at 15q21.3.
Gene Name: Unc-13 Homolog C
Chromosome: CHR15: 54305100 -54920806
Locus: 15q21.3
Gene Diseases
The TRIOBP UNC13C Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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