TRIOBP-CDC42EP1 Fusion FISH Probe
The TRIOBP-CDC42EP1 Fusion FISH Probe is used to confirm a fusion of the TRIOBP and CDC42EP1 genes. The fusion of the TRIOBP and CDC42EP1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIOBP-CDC42EP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-RERE | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-REOR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-REGO | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-REGR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-OROR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GORE | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GROR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIOBP-CDC42EP1-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIOBP Gene Summary
This gene encodes a protein with an N-terminal pleckstrin homology domain and a C-terminal coiled-coil region. The protein interacts with trio, which is involved with neural tissue development and controlling actin cytoskeleton organization, cell motility and cell growth. The protein also associates with F-actin and stabilizes F-actin structures. Mutations in this gene have been associated with a form of autosomal recessive nonsyndromic deafness. Multiple alternatively spliced transcript variants that would encode different isoforms have been found for this gene, however some transcripts may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Nov 2008]
Gene Name: TRIO And F-actin Binding Protein
Chromosome: CHR22: 38092994 -38172563
Locus: 22q13.1
CDC42EP1 Gene Summary
CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008]
Gene Name: CDC42 Effector Protein 1
Chromosome: CHR22: 37956470 -37965410
Locus: 22q13.1
Gene Diseases
The TRIOBP CDC42EP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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