TRIO-PPP2R5E Fusion FISH Probe
The TRIO-PPP2R5E Fusion FISH Probe is used to confirm a fusion of the TRIO and PPP2R5E genes. The fusion of the TRIO and PPP2R5E genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIO-PPP2R5E-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-RERE | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-REOR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-REGO | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-REGR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-OROR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GORE | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GROR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIO-PPP2R5E-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R5E Gene Summary
The protein encoded by this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an epsilon isoform of the regulatory subunit B56 subfamily. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'epsilon
Chromosome: CHR14: 63841354 -64010079
Locus: 14q23.2
TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
Gene Diseases
The TRIO PPP2R5E Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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