TRIO-KDSR Fusion FISH Probe
The TRIO-KDSR Fusion FISH Probe is used to confirm a fusion of the TRIO and KDSR genes. The fusion of the TRIO and KDSR genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIO-KDSR-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-RERE | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-REOR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-REGO | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-REGR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-OROR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GORE | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GROR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIO-KDSR-20-AQAQ | 20 (40 μL) | 200 μL |
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KDSR Gene Summary
The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy. [provided by RefSeq, Jul 2008]
Gene Name: 3-ketodihydrosphingosine Reductase
Chromosome: CHR18: 60994970 -61034506
Locus: 18q21.33
TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
Gene Diseases
The TRIO KDSR Fusion has been associated with the following diseases:
| Disease Name |
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| Colon Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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