TRIO-CDH18 Fusion FISH Probe
The TRIO-CDH18 Fusion FISH Probe is used to confirm a fusion of the TRIO and CDH18 genes. The fusion of the TRIO and CDH18 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TRIO-CDH18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TRIO-CDH18-20-AQAQ | 20 (40 μL) | 200 μL |
|
CDH18 Gene Summary
This gene encodes a type II classical cadherin from the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed specifically in the central nervous system and is putatively involved in synaptic adhesion, axon outgrowth and guidance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: Cadherin 18
Chromosome: CHR5: 19473154 -19988353
Locus: 5p14.3
TRIO Gene Summary
This gene encodes a large protein that functions as a GDP to GTP exchange factor. This protein promotes the reorganization of the actin cytoskeleton, thereby playing a role in cell migration and growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Gene Name: Trio Rho Guanine Nucleotide Exchange Factor
Chromosome: CHR5: 14143828 -14509458
Locus: 5p15.2
Gene Diseases
The TRIO CDH18 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|