TRIM4-TAF6 Fusion FISH Probe
The TRIM4-TAF6 Fusion FISH Probe is used to confirm a fusion of the TRIM4 and TAF6 genes. The fusion of the TRIM4 and TAF6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIM4-TAF6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-RERE | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-REOR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-OROR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GORE | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIM4-TAF6-20-AQAQ | 20 (40 μL) | 200 μL |
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TAF6 Gene Summary
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]
Gene Name: TATA-box Binding Protein Associated Factor 6
Chromosome: CHR7: 99704692 -99717481
Locus: 7q22.1
TRIM4 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that encode different isoforms have been described.[provided by RefSeq, Jul 2010]
Gene Name: Tripartite Motif Containing 4
Chromosome: CHR7: 99488029 -99517223
Locus: 7q22.1
Gene Diseases
The TRIM4 TAF6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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