TRIM26-DHX16 Fusion FISH Probe
The TRIM26-DHX16 Fusion FISH Probe is used to confirm a fusion of the TRIM26 and DHX16 genes. The fusion of the TRIM26 and DHX16 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIM26-DHX16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-RERE | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-REOR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-OROR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GORE | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIM26-DHX16-20-AQAQ | 20 (40 μL) | 200 μL |
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TRIM26 Gene Summary
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
Gene Name: Tripartite Motif Containing 26
Chromosome: CHR6_qbl_hap6: 1445146 -1474192
Locus: 6p22.1
DHX16 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a functional homolog of fission yeast Prp8 protein involved in cell cycle progression. This gene is mapped to the MHC region on chromosome 6p21.3, a region where many malignant, genetic and autoimmune disease genes are linked. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Name: DEAH-box Helicase 16
Chromosome: CHR6_ssto_hap7: 1953167 -1973134
Locus: 6p21.33
Gene Diseases
The TRIM26 DHX16 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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