TRIM24-NTRK2 Fusion FISH Probe
The TRIM24-NTRK2 Fusion FISH Probe is used to confirm a fusion of the TRIM24 and NTRK2 genes. The fusion of the TRIM24 and NTRK2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRIM24-NTRK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-RERE | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-REOR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-REGO | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-REGR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-REAQ | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-ORRE | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-OROR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-ORGO | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GORE | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GOOR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GOGO | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GOGR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GRRE | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GROR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GRGO | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GRGR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-AQRE | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-AQOR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-AQGO | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-AQGR | 20 (40 μL) | 200 μL |
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| TRIM24-NTRK2-20-AQAQ | 20 (40 μL) | 200 μL |
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NTRK2 Gene Summary
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
Gene Name: Neurotrophic Receptor Tyrosine Kinase 2
Chromosome: CHR9: 87283465 -87638505
Locus: 9q21.33
TRIM24 Gene Summary
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tripartite Motif Containing 24
Chromosome: CHR7: 138145078 -138270332
Locus: 7q33-q34
Gene Diseases
The TRIM24 NTRK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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