TRERF1-GNMT Fusion FISH Probe
The TRERF1-GNMT Fusion FISH Probe is used to confirm a fusion of the TRERF1 and GNMT genes. The fusion of the TRERF1 and GNMT genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRERF1-GNMT-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-RERE | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-REOR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-REGO | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-REGR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-REAQ | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-ORRE | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-OROR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-ORGO | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GORE | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GOOR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GOGO | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GOGR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GRRE | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GROR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GRGO | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GRGR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-AQRE | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-AQOR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-AQGO | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-AQGR | 20 (40 μL) | 200 μL |
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| TRERF1-GNMT-20-AQAQ | 20 (40 μL) | 200 μL |
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GNMT Gene Summary
The protein encoded by this gene is an enzyme that catalyzes the conversion of S-adenosyl-L-methionine (along with glycine) to S-adenosyl-L-homocysteine and sarcosine. This protein is found in the cytoplasm and acts as a homotetramer. Defects in this gene are a cause of GNMT deficiency (hypermethioninemia). Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between the upstream CNPY3 (canopy FGF signaling regulator 3) gene and this gene and is represented with GeneID:107080644. [provided by RefSeq, Jan 2016]
Gene Name: Glycine N-methyltransferase
Chromosome: CHR6: 42928499 -42931618
Locus: 6p21.1
TRERF1 Gene Summary
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
Gene Name: Transcriptional Regulating Factor 1
Chromosome: CHR6: 42192668 -42419783
Locus: 6p21.1
Gene Diseases
The TRERF1 GNMT Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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