TRAPPC10-BRWD1 Fusion FISH Probe
The TRAPPC10-BRWD1 Fusion FISH Probe is used to confirm a fusion of the TRAPPC10 and BRWD1 genes. The fusion of the TRAPPC10 and BRWD1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TRAPPC10-BRWD1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-RERE | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-REOR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-REGO | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-REGR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-REAQ | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-ORRE | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-OROR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-ORGO | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GORE | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GOOR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GOGO | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GOGR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GRRE | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GROR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GRGO | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GRGR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-AQRE | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-AQOR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-AQGO | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-AQGR | 20 (40 μL) | 200 μL |
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| TRAPPC10-BRWD1-20-AQAQ | 20 (40 μL) | 200 μL |
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TRAPPC10 Gene Summary
The protein encoded by this gene is a transmembrane protein found in the cis-Golgi complex. The encoded protein is part of the multisubunit transport protein particle (TRAPP) complex and may be involved in vesicular transport from the endoplasmic reticulum to the Golgi. Mutations in this gene could be responsible for the Unverricht-Lundborg type of progressive myoclonus epilepsy, or for autoimmune polyglandular disease type 1. [provided by RefSeq, Jul 2008]
Gene Name: Trafficking Protein Particle Complex 10
Chromosome: CHR21: 45432205 -45526432
Locus: 21q22.3
BRWD1 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain which may regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex.[provided by RefSeq, Jun 2011]
Gene Name: Bromodomain And WD Repeat Domain Containing 1
Chromosome: CHR21: 40557403 -40685712
Locus: 21q22.2
Gene Diseases
The TRAPPC10 BRWD1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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