TPX2-DEFB118 Fusion FISH Probe
The TPX2-DEFB118 Fusion FISH Probe is used to confirm a fusion of the TPX2 and DEFB118 genes. The fusion of the TPX2 and DEFB118 genes has been associated with Uterine Carcinosarcoma, and Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPX2-DEFB118-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TPX2-DEFB118-20-AQAQ | 20 (40 μL) | 200 μL |
|
TPX2 Gene Summary
The TPX2, Microtubule Nucleation Factor (TPX2) gene is located on chr20 :30326903-30389603 at 20q11.21.
Gene Name: TPX2, Microtubule Nucleation Factor
Chromosome: CHR20: 30326903 -30389603
Locus: 20q11.21
DEFB118 Gene Summary
This gene encodes a member of the beta subfamily of defensins. Beta-defensins are antimicrobial peptides that protect tissues and organs from infection by a variety of microorganisms. Expression of this gene is regulated by androgen, and the encoded protein binds to sperm and exhibits antibacterial activity against E. coli. This gene is found in a cluster with other beta-defensin genes on the long arm of chromosome 20. [provided by RefSeq, Nov 2014]
Gene Name: Defensin Beta 118
Chromosome: CHR20: 29956420 -29961705
Locus: 20q11.21
Gene Diseases
The TPX2 DEFB118 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Carcinosarcoma |
| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|