TPX2-ACLY Fusion FISH Probe
The TPX2-ACLY Fusion FISH Probe is used to confirm a fusion of the TPX2 and ACLY genes. The fusion of the TPX2 and ACLY genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TPX2-ACLY-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-RERE | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-REOR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-REGO | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-REGR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-REAQ | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-ORRE | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-OROR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-ORGO | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-ORAQ | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GORE | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GOOR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GOGO | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GOGR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GOAQ | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GRRE | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GROR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GRGO | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GRGR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-GRAQ | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-AQRE | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-AQOR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-AQGO | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-AQGR | 20 (40 μL) | 200 μL |
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| TPX2-ACLY-20-AQAQ | 20 (40 μL) | 200 μL |
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ACLY Gene Summary
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014]
Gene Name: ATP Citrate Lyase
Chromosome: CHR17: 40023178 -40075272
Locus: 17q21.2
TPX2 Gene Summary
The TPX2, Microtubule Nucleation Factor (TPX2) gene is located on chr20 :30326903-30389603 at 20q11.21.
Gene Name: TPX2, Microtubule Nucleation Factor
Chromosome: CHR20: 30326903 -30389603
Locus: 20q11.21
Gene Diseases
The TPX2 ACLY Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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