TPT1-PEX1 Fusion FISH Probe
The TPT1-PEX1 Fusion FISH Probe is used to confirm a fusion of the TPT1 and PEX1 genes. The fusion of the TPT1 and PEX1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TPT1-PEX1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-RERE | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-REOR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-REGO | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-REGR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-REAQ | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-ORRE | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-OROR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-ORGO | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GORE | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GOOR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GOGO | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GOGR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GRRE | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GROR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GRGO | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GRGR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-AQRE | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-AQOR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-AQGO | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-AQGR | 20 (40 μL) | 200 μL |
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| TPT1-PEX1-20-AQAQ | 20 (40 μL) | 200 μL |
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PEX1 Gene Summary
This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]
Gene Name: Peroxisomal Biogenesis Factor 1
Chromosome: CHR7: 92116336 -92157845
Locus: 7q21.2
TPT1 Gene Summary
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Name: Tumor Protein, Translationally-controlled 1
Chromosome: CHR13: 45911303 -45915297
Locus: 13q14.13
Gene Diseases
The TPT1 PEX1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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