TPT1-DDX27 Fusion FISH Probe
The TPT1-DDX27 Fusion FISH Probe is used to confirm a fusion of the TPT1 and DDX27 genes. The fusion of the TPT1 and DDX27 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TPT1-DDX27-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TPT1-DDX27-20-AQAQ | 20 (40 μL) | 200 μL |
|
TPT1 Gene Summary
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Gene Name: Tumor Protein, Translationally-controlled 1
Chromosome: CHR13: 45911303 -45915297
Locus: 13q14.13
DDX27 Gene Summary
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein involved in the processing of 5.8S and 28S ribosomal RNAs. More specifically, the encoded protein localizes to the nucleolus, where it interacts with the PeBoW complex to ensure proper 3' end formation of 47S rRNA. [provided by RefSeq, Jan 2017]
Gene Name: DEAD-box Helicase 27
Chromosome: CHR20: 47835831 -47860614
Locus: 20q13.13
Gene Diseases
The TPT1 DDX27 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|