TPCN2-TMEM179B Fusion FISH Probe
The TPCN2-TMEM179B Fusion FISH Probe is used to confirm a fusion of the TPCN2 and TMEM179B genes. The fusion of the TPCN2 and TMEM179B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TPCN2-TMEM179B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-RERE | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-REOR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-REGO | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-REGR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-REAQ | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-ORRE | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-OROR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-ORGO | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-ORAQ | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GORE | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GOOR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GOGO | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GOGR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GOAQ | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GRRE | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GROR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GRGO | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GRGR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-GRAQ | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-AQRE | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-AQOR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-AQGO | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-AQGR | 20 (40 μL) | 200 μL |
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| TPCN2-TMEM179B-20-AQAQ | 20 (40 μL) | 200 μL |
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TPCN2 Gene Summary
This gene encodes a putative cation-selective ion channel with two repeats of a six-transmembrane-domain. The protein localizes to lysosomal membranes and enables nicotinic acid adenine dinucleotide phosphate (NAADP) -induced calcium ion release from lysosome-related stores. This ubiquitously expressed gene has elevated expression in liver and kidney. Two common nonsynonymous SNPs in this gene strongly associate with blond versus brown hair pigmentation.[provided by RefSeq, Dec 2009]
Gene Name: Two Pore Segment Channel 2
Chromosome: CHR11: 68816349 -68858072
Locus: 11q13.3
TMEM179B Gene Summary
The Transmembrane Protein 179B (TMEM179B) gene is located on chr11 :62554873-62557872 at 11q12.3.
Gene Name: Transmembrane Protein 179B
Chromosome: CHR11: 62554873 -62557872
Locus: 11q12.3
Gene Diseases
The TPCN2 TMEM179B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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