SEARCH OUR PRODUCT CATALOG

TP53BP1-ATP8B4 Fusion FISH Probe

The TP53BP1-ATP8B4 Fusion FISH Probe is used to confirm a fusion of the TP53BP1 and ATP8B4 genes. The fusion of the TP53BP1 and ATP8B4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TP53BP1-ATP8B4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-RERE 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-REOR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-REGO 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-REGR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-REAQ 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-ORRE 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-OROR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-ORGO 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-ORAQ 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GORE 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GOOR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GOGO 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GOGR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GOAQ 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GRRE 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GROR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GRGO 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GRGR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-GRAQ 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-AQRE 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-AQOR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-AQGO 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-AQGR 20 (40 μL) 200 μL
TP53BP1-ATP8B4-20-AQAQ 20 (40 μL) 200 μL

TP53BP1 Gene Summary

This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]

Gene Name: Tumor Protein P53 Binding Protein 1

Chromosome: CHR15: 43699411 -43802707

Locus: 15q15.3

ATP8B4 Gene Summary

This gene encodes a member of the cation transport ATPase (P-type) family and type IV subfamily. The encoded protein is involved in phospholipid transport in the cell membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

Gene Name: ATPase Phospholipid Transporting 8B4 (putative)

Chromosome: CHR15: 50150434 -50411419

Locus: 15q21.2

Gene Diseases

The TP53BP1 ATP8B4 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.