TP53-KIAA0753 Fusion FISH Probe
The TP53-KIAA0753 Fusion FISH Probe is used to confirm a fusion of the TP53 and KIAA0753 genes. The fusion of the TP53 and KIAA0753 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TP53-KIAA0753-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-RERE | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-REOR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-REGO | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-REGR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-REAQ | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-ORRE | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-OROR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-ORGO | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-ORAQ | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GORE | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GOOR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GOGO | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GOGR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GOAQ | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GRRE | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GROR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GRGO | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GRGR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-GRAQ | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-AQRE | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-AQOR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-AQGO | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-AQGR | 20 (40 μL) | 200 μL |
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| TP53-KIAA0753-20-AQAQ | 20 (40 μL) | 200 μL |
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TP53 Gene Summary
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons from identical transcript variants (PMIDs: 12032546, 20937277). [provided by RefSeq, Dec 2016]
Gene Name: Tumor Protein P53
Chromosome: CHR17: 7571719 -7590863
Locus: 17p13.1
KIAA0753 Gene Summary
This gene encodes a subunit of a protein complex that regulates ciliogenesis and cilia maintenance. The encoded protein has also been shown to regulate centriolar duplication. Mutations in this gene cause an orofaciodigital syndrome and a form of Joubert syndrome in human patients. [provided by RefSeq, May 2017]
Gene Name:
Chromosome: CHR17: 6481644 -6544247
Locus: 17p13.1
Gene Diseases
The TP53 KIAA0753 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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