TOX3-CNTN5 Fusion FISH Probe
The TOX3-CNTN5 Fusion FISH Probe is used to confirm a fusion of the TOX3 and CNTN5 genes. The fusion of the TOX3 and CNTN5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOX3-CNTN5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-RERE | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-REOR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-REGO | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-REGR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-REAQ | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-ORRE | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-OROR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-ORGO | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-ORAQ | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GORE | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GOOR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GOGO | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GOGR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GOAQ | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GRRE | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GROR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GRGO | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GRGR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-GRAQ | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-AQRE | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-AQOR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-AQGO | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-AQGR | 20 (40 μL) | 200 μL |
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| TOX3-CNTN5-20-AQAQ | 20 (40 μL) | 200 μL |
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TOX3 Gene Summary
The protein encoded by this gene contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2009]
Gene Name: TOX High Mobility Group Box Family Member 3
Chromosome: CHR16: 52471917 -52581714
Locus: 16q12.1
CNTN5 Gene Summary
The protein encoded by this gene is a member of the immunoglobulin superfamily, and contactin family, which mediate cell surface interactions during nervous system development. This protein is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: Contactin 5
Chromosome: CHR11: 98891705 -100229616
Locus: 11q22.1
Gene Diseases
The TOX3 CNTN5 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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