TOP3A-ANAPC16 Fusion FISH Probe
The TOP3A-ANAPC16 Fusion FISH Probe is used to confirm a fusion of the TOP3A and ANAPC16 genes. The fusion of the TOP3A and ANAPC16 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOP3A-ANAPC16-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-RERE | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-REOR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-REGO | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-REGR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-REAQ | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-ORRE | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-OROR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-ORGO | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-ORAQ | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GORE | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GOOR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GOGO | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GOGR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GOAQ | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GRRE | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GROR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GRGO | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GRGR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-GRAQ | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-AQRE | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-AQOR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-AQGO | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-AQGR | 20 (40 μL) | 200 μL |
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| TOP3A-ANAPC16-20-AQAQ | 20 (40 μL) | 200 μL |
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TOP3A Gene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Name: DNA Topoisomerase III Alpha
Chromosome: CHR17: 18177234 -18218321
Locus: 17p11.2
ANAPC16 Gene Summary
The Anaphase Promoting Complex Subunit 16 (ANAPC16) gene is located on chr10 :73975757-73995618 at 10q22.1.
Gene Name: Anaphase Promoting Complex Subunit 16
Chromosome: CHR10: 73975757 -73995618
Locus: 10q22.1
Gene Diseases
The TOP3A ANAPC16 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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