TOP1-SLC2A10 Fusion FISH Probe
The TOP1-SLC2A10 Fusion FISH Probe is used to confirm a fusion of the TOP1 and SLC2A10 genes. The fusion of the TOP1 and SLC2A10 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOP1-SLC2A10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-RERE | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-REOR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-REGO | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-REGR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-REAQ | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-ORRE | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-OROR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-ORGO | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-ORAQ | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GORE | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GOOR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GOGO | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GOGR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GOAQ | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GRRE | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GROR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GRGO | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GRGR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-GRAQ | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-AQRE | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-AQOR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-AQGO | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-AQGR | 20 (40 μL) | 200 μL |
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| TOP1-SLC2A10-20-AQAQ | 20 (40 μL) | 200 μL |
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TOP1 Gene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
Gene Name: DNA Topoisomerase I
Chromosome: CHR20: 39657461 -39753126
Locus: 20q12
SLC2A10 Gene Summary
This gene encodes a member of the class III facilitative glucose transporter family. The encoded protein plays a role in regulation of glucose homeostasis. Mutations in this gene have been associated with arterial tortuosity syndrome.[provided by RefSeq, Dec 2009]
Gene Name: Solute Carrier Family 2 Member 10
Chromosome: CHR20: 45338278 -45364985
Locus: 20q13.12
Gene Diseases
The TOP1 SLC2A10 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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