TOM1-ARFGEF2 Fusion FISH Probe
The TOM1-ARFGEF2 Fusion FISH Probe is used to confirm a fusion of the TOM1 and ARFGEF2 genes. The fusion of the TOM1 and ARFGEF2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TOM1-ARFGEF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-RERE | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-REOR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-REGO | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-REGR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-REAQ | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-ORRE | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-OROR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-ORGO | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GORE | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GOOR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GOGO | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GOGR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GRRE | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GROR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GRGO | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GRGR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-AQRE | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-AQOR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-AQGO | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-AQGR | 20 (40 μL) | 200 μL |
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| TOM1-ARFGEF2-20-AQAQ | 20 (40 μL) | 200 μL |
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TOM1 Gene Summary
This gene was identified as a target of the v-myb oncogene. The encoded protein shares its N-terminal domain in common with proteins associated with vesicular trafficking at the endosome. It is recruited to the endosomes by its interaction with endofin. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Gene Name: Target Of Myb1 Membrane Trafficking Protein
Chromosome: CHR22: 35695267 -35743987
Locus: 22q12.3
ARFGEF2 Gene Summary
ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008]
Gene Name: ADP Ribosylation Factor Guanine Nucleotide Exchange Factor 2
Chromosome: CHR20: 47538274 -47653230
Locus: 20q13.13
Gene Diseases
The TOM1 ARFGEF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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