TNS4-CCR7 Fusion FISH Probe
The TNS4-CCR7 Fusion FISH Probe is used to confirm a fusion of the TNS4 and CCR7 genes. The fusion of the TNS4 and CCR7 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNS4-CCR7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-RERE | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-REOR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-REGO | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-REGR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-REAQ | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-ORRE | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-OROR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-ORGO | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GORE | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GOOR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GOGO | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GOGR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GRRE | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GROR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GRGO | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GRGR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-AQRE | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-AQOR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-AQGO | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-AQGR | 20 (40 μL) | 200 μL |
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| TNS4-CCR7-20-AQAQ | 20 (40 μL) | 200 μL |
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CCR7 Gene Summary
The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
Gene Name: C-C Motif Chemokine Receptor 7
Chromosome: CHR17: 38710021 -38721736
Locus: 17q21.2
TNS4 Gene Summary
The Tensin 4 (TNS4) gene is located on chr17 :38632079-38657854 at 17q21.2.
Gene Name: Tensin 4
Chromosome: CHR17: 38632079 -38657854
Locus: 17q21.2
Gene Diseases
The TNS4 CCR7 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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