TNS1-RNF25 Fusion FISH Probe
The TNS1-RNF25 Fusion FISH Probe is used to confirm a fusion of the TNS1 and RNF25 genes. The fusion of the TNS1 and RNF25 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNS1-RNF25-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TNS1-RNF25-20-AQAQ | 20 (40 μL) | 200 μL |
|
TNS1 Gene Summary
The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Gene Name: Tensin 1
Chromosome: CHR2: 218664511 -218808796
Locus: 2q35
RNF25 Gene Summary
The protein encoded by this gene contains a RING finger motif. The mouse counterpart of this protein has been shown to interact with Rela, the p65 subunit of NF-kappaB (NFKB), and modulate NFKB-mediated transcription activity. The mouse protein also binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination. [provided by RefSeq, Jul 2008]
Gene Name: Ring Finger Protein 25
Chromosome: CHR2: 219528586 -219536781
Locus: 2q35
Gene Diseases
The TNS1 RNF25 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|