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TNRC6B-SEMA6D Fusion FISH Probe

The TNRC6B-SEMA6D Fusion FISH Probe is used to confirm a fusion of the TNRC6B and SEMA6D genes. The fusion of the TNRC6B and SEMA6D genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TNRC6B-SEMA6D-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-RERE 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-REOR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-REGO 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-REGR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-REAQ 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-ORRE 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-OROR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-ORGO 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-ORAQ 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GORE 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GOOR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GOGO 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GOGR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GOAQ 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GRRE 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GROR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GRGO 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GRGR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-GRAQ 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-AQRE 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-AQOR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-AQGO 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-AQGR 20 (40 μL) 200 μL
TNRC6B-SEMA6D-20-AQAQ 20 (40 μL) 200 μL

TNRC6B Gene Summary

The Trinucleotide Repeat Containing 6B (TNRC6B) gene is located on chr22 :40440820-40731812 at 22q13.1.

Gene Name: Trinucleotide Repeat Containing 6B

Chromosome: CHR22: 40440820 -40731812

Locus: 22q13.1

SEMA6D Gene Summary

Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]

Gene Name: Semaphorin 6D

Chromosome: CHR15: 47476402 -48066420

Locus: 15q21.1

Gene Diseases

The TNRC6B SEMA6D Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.