TNRC6B-PES1 Fusion FISH Probe
The TNRC6B-PES1 Fusion FISH Probe is used to confirm a fusion of the TNRC6B and PES1 genes. The fusion of the TNRC6B and PES1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TNRC6B-PES1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| TNRC6B-PES1-20-AQAQ | 20 (40 μL) | 200 μL |
|
TNRC6B Gene Summary
The Trinucleotide Repeat Containing 6B (TNRC6B) gene is located on chr22 :40440820-40731812 at 22q13.1.
Gene Name: Trinucleotide Repeat Containing 6B
Chromosome: CHR22: 40440820 -40731812
Locus: 22q13.1
PES1 Gene Summary
This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9. [provided by RefSeq, Aug 2011]
Gene Name: Pescadillo Ribosomal Biogenesis Factor 1
Chromosome: CHR22: 30972611 -31003000
Locus: 22q12.2
Gene Diseases
The TNRC6B PES1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|