TNRC6B-ATXN10 Fusion FISH Probe
The TNRC6B-ATXN10 Fusion FISH Probe is used to confirm a fusion of the TNRC6B and ATXN10 genes. The fusion of the TNRC6B and ATXN10 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNRC6B-ATXN10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-RERE | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-REOR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-REGO | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-REGR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-REAQ | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-ORRE | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-OROR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-ORGO | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GORE | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GOOR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GOGO | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GOGR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GRRE | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GROR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GRGO | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GRGR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-AQRE | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-AQOR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-AQGO | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-AQGR | 20 (40 μL) | 200 μL |
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| TNRC6B-ATXN10-20-AQAQ | 20 (40 μL) | 200 μL |
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TNRC6B Gene Summary
The Trinucleotide Repeat Containing 6B (TNRC6B) gene is located on chr22 :40440820-40731812 at 22q13.1.
Gene Name: Trinucleotide Repeat Containing 6B
Chromosome: CHR22: 40440820 -40731812
Locus: 22q13.1
ATXN10 Gene Summary
This gene encodes a protein that may function in neuron survival, neuron differentiation, and neuritogenesis. These roles may be carried out via activation of the mitogen-activated protein kinase cascade. Expansion of an ATTCT repeat from 9-32 copies to 800-4500 copies in an intronic region of this locus has been associated with spinocerebellar ataxia, type 10. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jul 2016]
Gene Name: Ataxin 10
Chromosome: CHR22: 46067677 -46241187
Locus: 22q13.31
Gene Diseases
The TNRC6B ATXN10 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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