TNRC18-MKLN1 Fusion FISH Probe
The TNRC18-MKLN1 Fusion FISH Probe is used to confirm a fusion of the TNRC18 and MKLN1 genes. The fusion of the TNRC18 and MKLN1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNRC18-MKLN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-RERE | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-REOR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-REGO | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-REGR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-REAQ | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-ORRE | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-OROR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-ORGO | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GORE | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GOOR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GOGO | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GOGR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GRRE | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GROR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GRGO | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GRGR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-AQRE | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-AQOR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-AQGO | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-AQGR | 20 (40 μL) | 200 μL |
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| TNRC18-MKLN1-20-AQAQ | 20 (40 μL) | 200 μL |
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MKLN1 Gene Summary
Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]
Gene Name: Muskelin 1
Chromosome: CHR7: 130794854 -131181398
Locus: 7q32.3
TNRC18 Gene Summary
The Trinucleotide Repeat Containing 18 (TNRC18) gene is located on chr7 :5346422-5463177 at 7p22.1.
Gene Name: Trinucleotide Repeat Containing 18
Chromosome: CHR7: 5346422 -5463177
Locus: 7p22.1
Gene Diseases
The TNRC18 MKLN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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