TNPO3-DYM Fusion FISH Probe
The TNPO3-DYM Fusion FISH Probe is used to confirm a fusion of the TNPO3 and DYM genes. The fusion of the TNPO3 and DYM genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNPO3-DYM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-RERE | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-REOR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-REGO | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-REGR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-REAQ | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-ORRE | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-OROR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-ORGO | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GORE | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GOOR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GOGO | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GOGR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GRRE | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GROR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GRGO | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GRGR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-AQRE | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-AQOR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-AQGO | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-AQGR | 20 (40 μL) | 200 μL |
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| TNPO3-DYM-20-AQAQ | 20 (40 μL) | 200 μL |
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TNPO3 Gene Summary
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
Gene Name: Transportin 3
Chromosome: CHR7: 128594233 -128695227
Locus: 7q32.1
DYM Gene Summary
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
Gene Name: Dymeclin
Chromosome: CHR18: 46570171 -46987079
Locus: 18q21.1
Gene Diseases
The TNPO3 DYM Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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