TNPO2-HOOK2 Fusion FISH Probe
The TNPO2-HOOK2 Fusion FISH Probe is used to confirm a fusion of the TNPO2 and HOOK2 genes. The fusion of the TNPO2 and HOOK2 genes has been associated with Lung Squamous Cell Carcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNPO2-HOOK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-RERE | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-REOR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-REGO | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-REGR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-REAQ | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-ORRE | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-OROR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-ORGO | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GORE | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GOOR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GOGO | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GOGR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GRRE | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GROR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GRGO | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GRGR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-AQRE | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-AQOR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-AQGO | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-AQGR | 20 (40 μL) | 200 μL |
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| TNPO2-HOOK2-20-AQAQ | 20 (40 μL) | 200 μL |
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HOOK2 Gene Summary
Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004]
Gene Name: Hook Microtubule Tethering Protein 2
Chromosome: CHR19: 12873816 -12886434
Locus: 19p13.13
TNPO2 Gene Summary
The Transportin 2 (TNPO2) gene is located on chr19 :12810007-12834810 at 19p13.13.
Gene Name: Transportin 2
Chromosome: CHR19: 12810007 -12834810
Locus: 19p13.13
Gene Diseases
The TNPO2 HOOK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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