TNPO2-DNASE2 Fusion FISH Probe
The TNPO2-DNASE2 Fusion FISH Probe is used to confirm a fusion of the TNPO2 and DNASE2 genes. The fusion of the TNPO2 and DNASE2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNPO2-DNASE2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-RERE | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-REOR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-REGO | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-REGR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-REAQ | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-ORRE | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-OROR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-ORGO | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GORE | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GOOR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GOGO | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GOGR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GRRE | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GROR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GRGO | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GRGR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-AQRE | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-AQOR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-AQGO | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-AQGR | 20 (40 μL) | 200 μL |
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| TNPO2-DNASE2-20-AQAQ | 20 (40 μL) | 200 μL |
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DNASE2 Gene Summary
This gene encodes a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record. [provided by RefSeq, Jul 2008]
Gene Name: Deoxyribonuclease 2, Lysosomal
Chromosome: CHR19: 12986024 -12992335
Locus: 19p13.13
TNPO2 Gene Summary
The Transportin 2 (TNPO2) gene is located on chr19 :12810007-12834810 at 19p13.13.
Gene Name: Transportin 2
Chromosome: CHR19: 12810007 -12834810
Locus: 19p13.13
Gene Diseases
The TNPO2 DNASE2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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