TNNI3-ZNF607 Fusion FISH Probe
The TNNI3-ZNF607 Fusion FISH Probe is used to confirm a fusion of the TNNI3 and ZNF607 genes. The fusion of the TNNI3 and ZNF607 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNNI3-ZNF607-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-RERE | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-REOR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-REGO | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-REGR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-REAQ | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-ORRE | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-OROR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-ORGO | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GORE | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GOOR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GOGO | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GOGR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GRRE | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GROR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GRGO | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GRGR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-AQRE | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-AQOR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-AQGO | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-AQGR | 20 (40 μL) | 200 μL |
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| TNNI3-ZNF607-20-AQAQ | 20 (40 μL) | 200 μL |
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TNNI3 Gene Summary
Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul 2008]
Gene Name: Troponin I3, Cardiac Type
Chromosome: CHR19: 55663135 -55669100
Locus: 19q13.42
ZNF607 Gene Summary
The Zinc Finger Protein 607 (ZNF607) gene is located on chr19 :38187263-38210691 at 19q13.12.
Gene Name: Zinc Finger Protein 607
Chromosome: CHR19: 38187263 -38210691
Locus: 19q13.12
Gene Diseases
The TNNI3 ZNF607 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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