TNKS-ASAH1 Fusion FISH Probe
The TNKS-ASAH1 Fusion FISH Probe is used to confirm a fusion of the TNKS and ASAH1 genes. The fusion of the TNKS and ASAH1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TNKS-ASAH1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-RERE | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-REOR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-REGO | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-REGR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-REAQ | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-ORRE | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-OROR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-ORGO | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-ORAQ | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GORE | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GOOR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GOGO | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GOGR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GOAQ | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GRRE | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GROR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GRGO | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GRGR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-GRAQ | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-AQRE | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-AQOR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-AQGO | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-AQGR | 20 (40 μL) | 200 μL |
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| TNKS-ASAH1-20-AQAQ | 20 (40 μL) | 200 μL |
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ASAH1 Gene Summary
This gene encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. Processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid. This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene are associated with the lysosomal storage disorder, Farber lipogranulomatosis, and a neuromuscular disorder, spinal muscular atrophy with progressive myoclonic epilepsy. [provided by RefSeq, Oct 2015]
Gene Name: N-acylsphingosine Amidohydrolase 1
Chromosome: CHR8: 17913924 -17942507
Locus: 8p22
TNKS Gene Summary
The Tankyrase (TNKS) gene is located on chr8 :9413444-9639856 at 8p23.1.
Gene Name: Tankyrase
Chromosome: CHR8: 9413444 -9639856
Locus: 8p23.1
Gene Diseases
The TNKS ASAH1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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